Will received his PhD from the University of Ottawa, garnering a Governor General’s Gold Medal for my thesis work on molecular mechanisms that regulate the self-renewal decision of muscle stem cells. His PhD work has led to noveladvances in treatments for Duchenne Muscular Dystrophy by stimulating muscle stem cells for regeneration. Will moved to the Bay Area and did his postdoctoral training with Dr. Helen Blau at Stanford University School of Medicine. Will was one of the first adoptersof multiplexed CODEX imaging and used it to study skeletal muscle regeneration and aging, developing new machine learning and neural network analyses pipelines to unravel the complex multicellular processes involved. Will started his lab at Sanford BurnhamPrebys at the end of 2022 focusing on inflammatory neuromuscular disorders and how the aging systemic environment causes muscles to become weak and frail. Our goal is to pinpoint systemic mechanisms of muscle wasting and to develop of novel treatments thatpromote neuromuscular regeneration and improve quality of life.
Spatial regulators of neuromuscular regeneration and aging
Development of spatial phenotyping approaches to discover mechanisms of tissue regeneration and identification of prostaglandin metabolism as a novel target to rejuvenate neuromuscular connectivity in aging.